After comes another quirk in the fixture schedule, Chelsea heading to Anfield with the opportunity to repeat 2014 and derail a Liverpool title bid.
The visitors began to dominate proceedings in the second half and eventually broke through in the 80th minute when Salah scored to end a goal drought that had lasted nearly eight weeks.
Here are five things we learned as Liverpool put the pressure back on Manchester City.
Liverpool boss Jurgen Klopp agreed with Salah's decision to keep the ball while lauding the "Egyptian King" for reaching the 50-goal milestone.
Henderson not only notched a goal but he tallied the assist for Salah's goal.
The Egypt global gathered the ball on the half way line as Liverpool attacked on the break. Jordan Henderson scored six minutes later when he Roberto Firmino's pass picked him out in the 18-yard box to finish off the Saints.
All in all, the margins are going to be so small in the title race this season as goal difference or a single point is very likely to decide where the PL trophy will go.
The Egypt worldwide had been stuck on 49 Premier League goals since the 26-year-old found the net in a 3-0 victory over Bournemouth at the start of February.
Subscribe to Squawka's Youtube channel here. Shane Long was outpacing Trent Alexander-Arnold in a couple of key moments. Luckily Liverpool have strength in depth and two second half substitutions were enough to stretch Southampton to their limits.
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Once Milner and Henderson were introduced in the 59th minute, Liverpool suddenly turned their play up a notch.
Their persistency paid off and Southampton were eventually worn out as Klopp's men fired in two late goals to grab all the points.
Then, as the clock ticked over into the 81st minute, Mohamed Salah went and did this...
Liverpool's Danny Ings, on loan at Southampton, could not play for the home team.
Going forward the Reds weren't much better on that flank. "It is only around us that it is a big thing, we don't really care but it is a nice moment, and a really good moment for him to score his first goal in a while".
"Honestly, every time I watch Liverpool play, even if Matip misses it or two full-backs aren't there because they've gone forward, he just seems to cover the whole back four". That was until tonight when he rose up to head in the Reds' crucial first-half equaliser.
The Premier League title race has looked like a two-horse race from nearly the first kick of a ball last August and as the run-in intensifies, Neville would likely prefer City to come out on top because he has grown accustomed to their recent success.
Liverpool's Mohamed Salah celebrates scoring their second goal at the St Mary's Stadium in Southampton on April 6, 2019.