Two children, siblings aged 3 and 8, were killed on Saturday when a tree fell on the auto in which they were sitting in Pollok, Texas, said a spokeswoman for the Angelina County Sheriff's Department.
"The storm is so vigorous that tornadoes are still possible after dark", Myers said.
The Angelina County Sheriff's Office says an 8-year-old and a 3-year-old died Saturday when the tree toppled onto the back of their family's auto in Lufkin while it was in motion.
Yezak says two of the people injured Saturday when a likely tornado touched down near the cities of Hearne and Franklin were taken to hospitals with non-life-threatening injuries.
The tornado watch is in effect through 3 a.m. Monday, the NWS said.
About 100 miles northeast of Franklin, at least one suspected tornado swept through an outdoor event at the Caddo Mounds State Historic Site.
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Winds of up to 60 miles per hour (96.56 kph) were reported in Cherokee County, Texas, damaging two homes in Alto but not injuring anyone. Damage to roofs, windows, and vehicles will occur.
To the north, dime-sized hail pounded the Dallas-Fort Worth area.
During a press conference, Monroe County Road Manager Sonny Clay said the fatality was of 95-year-old Roy Ratliff, who died when a tree fell on his trailer in Hamilton, Miss.
The large storm system also knocked out power to thousands and caused flash floods. Separately, one person died when a auto was submerged in floodwaters in Calhoun, also near Monroe.
As a strong upper level and surface low pressure system continues to rotate eastward through Texas on Saturday, clusters of thunderstorms developed Saturday morning across much of the state.
Near the Birmingham suburb of Hueytown, a county employee died after being struck by a vehicle while he was helping clear away trees about 2:15 a.m. Sunday, said Capt. David Agee of the Jefferson County Sheriff's Office.
Residents in parts of Pennsylvania, Ohio, West Virginia Georgia and Florida were encouraged to monitor weather bulletins throughout Sunday and to secure loose outdoor items.