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A dozen or more Government ministers could quit by the end of February if Theresa May refuses to extend the Brexit negotiating period, a leading Tory opponent of European Union withdrawal has said.

Former Tory Chancellor Kenneth Clarke described the prospect of a Government defeat on what should have been an innocuous vote as "a shambles".

Parliament "has passed legislation that we are leaving on 29 March and it put that date on the face of the bill by a large margin", Reuters quoted Barclay as saying in parliament. Theresa May can not keep on trying to run down the clock and hoping that something will turn up that will save the day and save her face.

Theresa May is facing another embarrassing defeat after Tory eurosceptics warned they would vote against a symbolic motion on Brexit this evening unless it keeps the option of no deal on the table.

MPs voted by 303 to 258 against a motion endorsing the Government's approach.

"What last night's vote was clearly about was the Labour Party playing politics because they made a decision to vote against what was an unharmful motion setting out that the Prime Minister needs more time to deal with the issues the House raised two weeks ago".

It also undermined May's pledge to the European Union that if it renegotiates its deal with Britain, she can get that revised agreement approved by parliament.

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Many back the fact it reiterates support for the direction agreed on January 29, when MPs supported an amendment authorising Mrs May to return to Brussels to renegotiate the controversial Irish backstop.

Number 10 said Mrs May spoke to the Polish President Mateusz Morawiecki, the Estonian Prime Minister Juri Ratas and the Lithuanian President Dalia Grybauskaite on Friday afternoon. "The legislation, frankly, takes precedence over that motion".

However the Commons also voted for a non-binding cross-party amendment rejecting a no-deal break with the EU. May's office also argued that the opposition were in effect making no deal more likely by opposing her plans to work on a Withdrawal Agreement.

Mr Baker said: "Where this deal to pass through Parliament with this backstop, the Government would subsequently collapse because the DUP will not be able to maintain confidence and supply if this deal goes through".

Theresa May has herself changed tact to warn of the threat to the union if the United Kingdom were to leave the EU without a deal.

Meanwhile, a cross-party initiative backed by Tory Anna Soubry and Labour's Chuka Umunna demands the government publish its most recent official briefing on the implications of a no-deal Brexit for business and trade.