The result allows second-placed Atletico Madrid, playing on Sunday, the chance to close the gap on leaders Barca to three points.
"I don't know exactly what he has", the Barca boss said in his post-match press conference after the Valencia draw.
"We will have to wait to see what medical staff say".
The immediate response from Barcelona was strong, with Messi and Philippe Coutinho only denied by last-ditch challenges after driving into unsafe positions, while the former also had a free kick saved by Neto in the eighth minute.
All eyes will be on Lionel Messi who has 19 goals in 19 league matches, as well as Coutinho who hit two goals last time out.
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Parejo doubled the advantage from the penalty spot after Roberto knocked down Wass trying to dispute a cross.
Gameiro netted the opener for Los Che in the 27th minute of the game.
Sloppy defending from Sergi Roberto gave Valencia a penalty seven minutes later and Parejo sent the effort past Ter Stegen for a two-goal cushion. "If he's in good shape, he'll play on Wednesday [against Madrid]".
Celta Vigo broke a five-match losing streak and escaped the relegation zone by beating Sevilla 1-0 at home thanks to Okay Yokuslu's second-half goal.
He then bagged his second goal just after the hour mark to level the game.
Valencia, who began the season in the Champions League but have had a haphazard campaign and are seventh in the standings, looked to be on their way to a third league win in six visits to the Nou Camp after making a flying start.
Real Sociedad defeated Athletic Bilbao 2-1 to deal its northern Basque Country rival its first defeat since the arrival of coach Gaizka Garitano.