Christian Kouame picked up a loose ball when Juve's defence assumed it was going out for a corner, and his cross was met by the unmarked Bessa, who headed home from six yards out.
Alexis was absent from the session ahead of Tuesday's Champions League clash with Juventus, throwing his participation in the game into doubt.
"It's simple", he told reporters. We played for 10 minutes and then started thinking about Manchester.
"We went from being frenetic to falling asleep and vice-versa".
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Ronaldo's only outing against Mourinho's United was in the 2017 UEFA Super Cup, featuring for seven minutes as a substitute in Madrid's 2-1 win. Nothing is guaranteed or won before we've stepped on to the pitch.
"We played, from a certain point of view, with our heads in Manchester".
Fabian Ruiz, an early replacement for injury victim Simone Verdi, opened the scoring just 14 minutes in, and Dries Mertens doubled the lead from the spot after Nicholas Opoku handled inside the area inside the final 10 minutes. The Argentine was on target for Barcelona in their 4-2 La Liga win against Sevilla.
The Curacao-born 18-year-old is considered, alongside Angel Gomes, to be United's most exciting academy product and he impressed on the club's tour to the United States last summer. The Italian champions, though, were allowed to fill the seats with local school children.
Ronaldo has thus far scored five goals and registered five assists in nine Serie A games.