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Roseanne Barr, seen here during an event last month, has offered several explanations for her tweet attacking Valerie Jarrett - including saying that she was influenced by the sleep aid Ambien.

The Rev. Al Sharpton, who appeared alongside Jarrett in the MSNBC town hall, had harsh words for Barr and for Trump, who he said had long engaged in "dog-whistling" to racists.

Barr had sparked outrage on Tuesday by suggesting that Jarrett, who was born in Iran and is African American, was the product of the "muslim brotherhood and planet of the apes" having "a baby".

Throughout the evening and into early Wednesday morning, Barr retweeted a slew of fans and supporters who have taken to Twitter with a #IStandWithRoseanne campaign demanding people boycott ABC, reinstate the show, and that networks fire other "racist" figures on TV including Joy Behar and Bill Maher.

Barr also said her firing "worked out" because she "would leave when they started to try to censor me".

"I would hope that she has the character to feel bad for her colleagues..."

Sanofi, the maker of Ambien, tweeted that "racism isn't a known side effect" of Ambien.

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The reboot of "Roseanne" has been a blockbuster hit for ABC, but that did not stop ABC Entertainment president Channing Dungey from canceling the show.

Ms Jarrett, 61, was a top aide for Mr Obama and also served as assistant to the president for public engagement and chair of the White House council on women and girls, as well as leading his transition team when he moved into the White House. She added that she "made a mistake I wish I hadn't but.don't defend it please". However, even if another network would be interested in picking up Roseanne, it doesn't seem likely that the entire cast would be on board to return.

"I think Joe Rogan is right about Ambien", Barr wrote in a since-deleted tweet Tuesday night.

Oh honey. You can't blame years of insanity on one pill.

"I'm fine", she said.

Jarrett's name came up in response to Twitter commentary that raised her name in relation to an Obama conspiracy theory. ABC parent company Disney owns a 30-percent stake in Hulu.

But, after her history of making controversial and bigoted statements, ABC and her co-stars are not the only ones abandoning ship once and for all.